We are delighted to announce that our latest review paper — “Capturing physiological hemodynamic flow and mechanosensitive cell signaling in vessel-on-a-chip platforms” — has just been published at Frontiers in Physiology, as part of the special Research Topic “Mechanotransduction in Vascular Development and Disease“.
In this paper — which is a collaboration between our lab and the lab of Dr. Mark Mondrinos in Tulane Dept. of Biomedical Engineering — we review mechanosensitive signaling in the vasculature, and then explore strategies and challenges for incorporating physiological hemodynamic flow in vessel-on-a-chip microphysiological systems.